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Our results suggest that kindlin-2 is a key promoter of lung fibroblast activation, collagen matrix synthesis and pulmonary fibrosis, underscoring the therapeutic potential of targeting the kindlin-2 signaling pathway for control of this deadly lung disease.Background There has been much debate as to the importance of mechanical bowel preparation (MBP) and oral antibiotic agents (OA prior to elective colorectal surgery over the past two decades. There is no consensus between international guidelines. Methods The Australia and New Zea