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h commensal bacterial content in drinking water may protect against allergic diseases. © 2020 John Wiley Sons Ltd.Transcription factors (TF) are essential for plant growth and development. Several legumes (e.g. soybean) are rich sources of protein and oil, with great economic relevance. Here we report a phylogenomic analysis of TF families in legumes and their potential association with important traits (e.g. nitrogen fixation). We used TF DNA-binding domains to systematically screen the genomes of 15 legume and 5 non-legume species. TF or