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The sensitivity of plasma connective tissue growth factor as a diagnostic biomarker for PH was 95%, and the specificity was 90% at a cut-off value ≥650 pg/mL. The predictive value of plasma connective tissue growth factor for adverse outcome had a sensitivity of 88% and a specificity of 83% at a cut-off value ≥1900 pg/mL. CONCLUSION Connective tissue growth factor is a promising biomarker with good diagnostic and predictive values in children with PH-related CHD.On December 31, 2019 the China National Health Commission (NHC) reported th