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CONCLUSIONS We found that patients with MetS were more likely to quit smoking than those without MetS. However, intervention is still needed, as numerous patients with MetS continued to smoke. Interventions that actively involve medical institutions or organizations are among the most effective approaches to promote smoking cessation in patients with MetS. In particular, women, farmers and current drinkers should be prioritized. © 2020 Park M.B. et al.INTRODUCTION Tobacco smoking is the largest preventable cause of global mortality,