https://www.selleckchem.com/pr....oducts/phorbol-12-my
We examine the nonequilibrium production of topological defects-braids-in semiflexible filament bundles under cycles of compression and tension. During these cycles, the period of compression facilitates the thermally activated pair production of braid/anti-braid pairs, which then may separate when the bundle is under tension. As a result, appropriately tuned alternating periods of compression and extension should lead to the proliferation of braid defects in a bundle so that the linear density of these pairs far