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Furthermore, QLQ-C30 global health status score at M6 and M12, QLQ-C30 functions score at M12 were increased, while QLQ-C30 symptoms score was of no difference at each time point in RTCP group compared with CCP group. Regarding survival profiles, Kaplan-Meier curves indicated that disease-free survival and overall survival were of no difference between two groups, further multivariate Cox's proportional hazard regression analysis also observed the same trends. RTCP effectively relieves anxiety and depression, improves QoL, but did not