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4 months (33-41.8) after surgery. From Kaplan-Meier estimates, 1-year and 5-year disease free survival was 90.9% (95% CI 85.6-96.4%) and 81% (95% CI 71.2-92.1%) respectively. The preoperative prolactinemia was the only significant preoperative predictive factor for remission (P 0.05). No severe complication was reported, with no anterior pituitary deficiency after surgery, one diabetes insipidus, and one postoperative cerebrospinal fluid leakage properly treated by muscle plasty. In well-selected microprolactinoma patients, pitui