https://2pcpainhibitor.com/inv....asion-behaviour-in-t
Neuronal accumulation of misfolded microtubule-associated protein tau is a characteristic of neuropathology in Alzheimer's disease condition, frontotemporal alzhiemer's disease, and other tauopathies, and has now been a therapeutic target. Microglia can spread tau pathology by secreting tau-containing exosomes, even though certain molecular target is yet to be identified for the therapeutic input. P2X purinoceptor 7 (P2RX7) is an ATP-gated cation channel, enriched in microglia and trigger