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e., at different levels of muscle contraction and for different numbers of discharges per position. The results demonstrate that the algorithm eliminates artifacts more effectively than any previously available method and does so without distorting the waveform of the signal. Graphical abstract The raw scanning-EMG signal, which can be composed by several discharges of the MU, is processed by the MMLSS algorithm so as to eliminate the artifact interference. Firstly, artifacts are detected for each discharge from the raw signal, obtain