https://www.selleckchem.com/pr....oducts/cbr-470-1.htm
Collagen α3 (IV) chains are one of the major constituent components of the basement membrane in the mammalian testis. Studies have shown that biologically active fragments, such as noncollagenase domain (NC1)-peptide, can be released from the C-terminal region of collagen α3 (IV) chains, possibly through the proteolytic action of metalloproteinase 9 (MMP9). NC1-peptide was shown to promote blood-testis barrier (BT remodeling and fully developed spermatid (e.g., sperm) release from the seminiferous epithelium because this bioactive p
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