https://www.selleckchem.com/pr....oducts/corticosteron
Diastereoselective Michael addition reactions of 3-(alkylamino)-9H-furo[3,4-b]chromen-9-one intermediate, produced from the [1 + 4] cycloaddition/tautomerization reaction between 3-formylchromones and alkyl isocyanide in dry CH2Cl2, with arylidene malononitrile were developed to afford a wide range of functionalized 2-((S)-((R,Z)-3-(alkylimino)-9-oxo-3,9-dihydro-1H-furo[3,4-b]chromen-1-yl)(aryl)methyl)malononitrile derivatives in good yields and excellent diastereoselectivities under mild conditions. Excellent diastereoselectivit
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