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© 2020 John Wiley Sons, Ltd.BACKGROUND Antiplatelet antibodies tend to be recognized in numerous conditions including main immune thrombocytopenia (ITP). Dynamics of how these antibodies change as time passes in ITP is unidentified in dogs. HYPOTHESIS/OBJECTIVES Antiplatelet antibodies (APA) may be detected in thrombocytopenic dogs with numerous etiologies and dynamics of APA in dogs with ITP may be used to evaluate reaction to therapy and relapse. Determine APA durin