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Perfusion images were calculated by subtracting the end-inspiratory precontrast CT from the deformably registered end-inspiratory postcontrast CT, yielding a map of local Hounsfield device enhancement as a surrogate for perfusion. Ventilation-perfusion coordinating, spatial heterogeneity, and gravitationally directed gradients were compared between two groups using a Wilcoxon rank-sum test. Outcomes The normal team had significantly higher Dice similarity coefficients for spatial ov