https://www.selleckchem.com/pr....oducts/ly-3475070.ht
Leber's hereditary optic neuropathy (LHON) is a mitochondrial neuropathy that causes acute vision loss. Idebenone, a short-chain ubiquinone analog that preserves mitochondrial function is thought to suppress disease progression in early-onset LHON patients. We investigated the effects of idebenone in Japanese LHON patients. Prospective, interventional, non-comparative study in patients with definite LHON diagnosis, under trial registration number UMIN000017939. Fifty-seven patients received 900 mg/day idebenone for 24 weeks. We measu
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