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Time to onset typically ranged from weeks to months but could occur more than a year later. Improvement or resolution upon discontinuation of the inciting drug was common. This was a retrospective analysis. Familiarity with the clinical features of PRs from cytokine-blocking antibodies may facilitate efficient recognition and management. Familiarity with the clinical features of PRs from cytokine-blocking antibodies may facilitate efficient recognition and management. The coronavirus disease 2019 pandemic has presented an enormous chal