https://hcvproteasesignal.com/....index.php/hydroxychl
Quantitative PCR and Western blot analysis showed that osteoblast marker proteins, including alkaline phosphatase (ALP), runt-related transcription aspect 2 (RUNX2) and osteocalcin (OCN) were dramatically upregulated by IGF-1 therapy, indicating IGF-1 induced osteogenic differentiation in BMMSCs. Interestingly, the appearance degrees of the sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) 3 and inositol-1,4,5-triphosphate receptor (IP3R) 2 were dramatically eleva