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The aim of this review is to investigate the use of 3D printing technologies for removable denture fabrication with a focus on the advantages, potentials, disadvantages and barriers. An electronic search of the English language literature from 1970 to March 2020 was carried out in databases such as PubMed/MEDLINE, Embase, Scopus, and Web of Science databases with applying the inclusion and exclusion criteria. The search was performed using a variety of keywords including 3D printing, rapid prototyping, additive manufacturing, dentures/