https://www.selleckchem.com/pr....oducts/H-89-dihydroc
BACKGROUND The interaction between early life viral respiratory illness and atopy in the genesis of asthma has been widely discussed in the literature as the 'two hit hypothesis'. OBJECTIVE The aim of this study was to synthesise evidence regarding the association of childhood viral respiratory illness and atopy in the development of persistent wheezing and asthma. METHODS A systematic review was performed, according to PRISMA guidelines. Human studies investigating early life associations between atopy and viral respirator