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Necrosectomy was not required in 18 patients (35%). There were no significant differences in mortality among the different treatment approaches (P less then 0.45). Overall success, morbidity, and mortality rates were 68.6%, 52.9%, and 7.8%, respectively. Conclusions The multimodal approach seems to be a rational and efficient strategy for the initial treatment of IPN.Objective The aim of the study was to evaluate efficacy of chemoembolization and radioembolization in treating patients with recurrent hypoglycemia secondary to metastatic