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It really is worth pointing aside that losartan enhanced the phrase of tight junction proteins ZO-1 and alleviated brain edema and blood mind buffer leakage. Additionally, losartan inhibited pro-inflammatory aspect TNF-α and enhance anti-inflammatory aspect IL-10. Taken together, our information demonstrated that losartan could increase the prognosis of TBI and may also be a promising therapeutic way of mitigating TBI.Background Benign paroxysmal positional vertigo (BPPV) is a self-limiting and rec