https://www.selleckchem.com/pr....oducts/shin1-rz-2994
With 50% ethanol solution, the DNA conformational transition passes through two steps (i) fast and constant-velocity contraction and (ii) relatively slow contraction from the free end. The first process is attributed to the B to A conformational transition by gradual dehydration. The second process is due to the coil-globule transition as the free end of DNA starts the contraction. This globular structure formation counteracts the shear force from the microfluids and decelerates the contraction velocity. This real-time observation
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