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The symptoms in this patient were relieved postoperatively. CEA is a biomarker commonly used in colorectal cancer, however its use as a prognostic value is still controversial. Recent studies demonstrate that CEA produced locally by tumor cells has a higher prognostic value compared to serum CEA. It is intended to determine whether there is an association between the CEA/tumor size ratio (CEA/ExT) and the pathological tumor response in patients with rectal adenocarcinoma (ADC), submitted to neoadjuvant chemoradiotherapy (N-CRT), follow