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Healing was monitored at 2 and 4 weeks post-op, and at the 8 week study endpoint. Animals demonstrated appropriate weight gain, no aspiration events, and audible phonation. Video laryngoscopy showed progressive healing with vascularization and re-epithelialization present at 4 weeks. On histology, there was no immune reaction to the implants and there was complete integration into host tissue with nerve and vascular ingrowth. This pilot study represents a first in which a transmural vertical partial laryngectomy was performed an