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Untreated ADHD in Adults Untreated ADHD can lead to a wide range of problems. These include financial difficulties and relationship issues, as well as substance abuse, and criminal behavior. In fact, one study found that over half of the people who were sentenced to prison for crimes had ADHD. People who suffer from untreated ADHD are also more likely to suffer from co-occurring mental health issues. These disorders can include anxiety and depression. Lack of awareness Adults