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ADHD Treatment For Adults - Stimulant Medication Adult ADHD is treated with stimulant medications such as dextroamphetamine and methylphenidate. These drugs regulate and boost levels of brain chemicals known as neurotransmitters. Antidepressants and nonstimulant medicines like atomoxetine may be prescribed when stimulants aren't suitable for the patient due to health problems or adverse effects. These medications work more slowly than stimulants and decrease the impulsivity and inattention