https://www.selleckchem.com/products/gdc-0068.html
The stromal compartment in the tendon was the main source of CCL20 in this model and accordingly, in vitro activated human tendon cells were able to produce this chemokine and to induce CCR6+ T cell migration, the latter of which could be blocked by CCL20LD. Our studies highlight the pathogenic role of CCR6-CCL20 axis in enthesitis and raise the prospect of a novel therapeutic approach for treating patients with PsO and PsA. Our studies highlight the pathogenic role of CCR6-CCL20 axis in enthesitis and raise the prospect of a novel the