https://www.selleckchem.com/pr....oducts/yap-tead-inhi
The reference population had a Ne of 123.5, a mean F of 0.095 (SD 0.082), 2276 founders (f), 205.5 effective founders (fe), 28 effective ancestors (fa) and 10.65 (SD 2.82) founder genomes (Ng). Removing TNS and NCL carriers from the genotyped population had a small impact on diversity measures (ROH 1 Mb, MLH, heterozygosity), however, there was a loss of 10% minor allele frequency for 89 SNPs around the TNS mutation (maximum loss of 12.7%), and a loss of 5% for 5 SNPs around the NCL mutation (maxim
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