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the stroke volume of the pump to be larger than 1 Hz. This opens avenues towards the development of new GPV, pump, and mixers in order to mix efficiently the solvent packets delivered by conventional LC instrument.Dual-channel chromatography was evaluated for pesticide residue analysis in fruits and vegetables and for unknown compounds detection. A dual-channel system was tested coupled to triple quadrupole and high-resolution mass spectrometry. The first part of the investigation was related to the improvement of the sample throughput w