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ART dramatically inhibited cellular proliferation in dose- and time-dependent ways. Collectively, the mixture therapy extremely reduced colony development rates and enhanced the rates of TUNEL-positive cells weighed against mono-treatment. Mechanistically, the blend treatment affected the phrase of Bcl-2, Bax, p-P53, Caspase-3/7, Caspase-9, CyclinB1, P34, P21, and synergistically managed the game of P38/JNK/ERK1/2 MAPK pathway. In mice A549 xenograft tumors, the blend strat