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05). UACR levels were significantly reduced at 3 months and 6 months after RDN ( 0.001). After RDN, the heart rate showed no significant changes ( 0.05), and few major complications were encountered. The meta-analysis showed that RDN may be effective and safe for treating CKD patients with hypertension. Well-designed randomized controlled trials of RDN are urgently needed to confirm the safety and reproducibility of RDN and to assess its impact on clinical outcomes. The meta-analysis showed that RDN may be effective and safe f