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The purpose of this article would be to review the present advances in ultrasound-assisted nano-emulsion synthesis and difficulties about the safety of the nano-emulsion. Application regarding the nano-emulsions within the various professional and medical procedures like medication distribution process, meals business, pesticide industry and cosmetic makeup products business are reviewed. Ultrasound-assisted synthesis of nano-emulsions easy technique than other synthesis types of the nanoemulsions. Nano