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Western blot analysis demonstrated the increased expression of mitochondrial function-related proteins and activation of mitochondrial apoptotic pathways. Hematoxylin and eosin staining and terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) assays revealed that the proportion of proapoptotic cells was significantly higher in rats that underwent CLP than sham surgery at 2 to 24 hours postoperatively. Taken together, our results indicate that-in the rat model-CLP-induced sepsis leads to impaired cardiac function. Further

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Children in this age range who are overweight/obese do not display impaired metabolic flexibility with respect to fat metabolism during exercise. Children in this age range who are overweight/obese do not display impaired metabolic flexibility with respect to fat metabolism during exercise. Contributions of neural and muscular factors to muscle strength change with growth, but such changes remain unclear in young populations. This study aimed to clarify the association between muscle strength and neural and muscular f