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6 µM). Interestingly, hybrid 1 shows also inhibitory activity against hepatitis B virus in vitro (EC50 (HBeAg) = 2.57 µM).Aim The purpose of this retrospective study was to perform an evaluation of postoperative positional changes of the condyle and mandibular function after bilateral sagittal split osteotomy (BSSO) with manual proximal segment positioning. Patients 45 patients were divided into the 2 groups ‒ G1 (advancement ‒ 14 patients) and G2 (setback - 31 patients). Rigid internal fixation screws were utilized in all cases. Inclu
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