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To investigate the use of a set of dynamical features, extracted from surface electromyography, to study upper motor neuron (UMN) degeneration in amyotrophic lateral sclerosis (ALS). We acquired surface EMG signals from the upper limb muscles of 13 ALS patients and 20 control subjects and classified them according to a novel set of muscle activity features, describing the temporal and frequency dynamic behavior of the signals, as well as measures of its complexity. Using a battery of classification approaches, we searched for the most d