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It will also help clinicians understand the current state of the management of CRSwNP and its gaps and be better able to interpret the new information to come. BACKGROUND Desloratadine is a frequently used drug for the treatment of allergic disorders, which often also require treatment during pregnancy. However, information on the fetal safety of desloratadine use during pregnancy is limited. OBJECTIVE To investigate the association between desloratadine use during pregnancy and adverse fetal outcomes. METHODS From a cohort of 1,287,668