https://www.selleckchem.com/pr....oducts/NVP-AUY922.ht
Neutralization of TNF, but not IL-6, prevented sensitization of the liver to hepatotoxicity induced with anti-CD40 in combination with chemotherapy without impacting antitumor efficacy. Our findings reveal a clinically feasible approach to mitigate toxicity without impairing efficacy in the use of agonist CD40 antibodies for cancer immunotherapy.Metal nanoclusters, also known as ultra-small metal nanoparticles, occupy the gap between discrete atoms and plasmonic nanomaterials, and are an emerging class of atomically precise nanomater