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1-3.1)] and 1 h mean difference 1.5 points (95%CI 0.7-2.2) after the procedure (p less then 0.03). Heart rate was lower (173(22) vs. 184(18)/min) and oxygen saturations were higher (93.8(6.2) vs. 91.7(6.1)%, p = 0.05) in MAA infants. No adverse effects. Interpretation MAA may reduce physiological pain responses during and after ROP exam in preterm infants. Assessment of long-term effects are warranted. Clinical trial registration www.ClinicalTrials.gov, identifier NCT03650621.Background Retinopathy of pre-maturity (ROP) is a disorder o
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