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There was an important improvement in both aural fullness and tinnitus for customers undergoing ESD with no unfavorable effect on audiologic condition. ESD is a practicable selection for treatment of Meniere's condition with vertigo, aural fullness, and tinnitus relief. Future prospective researches are required to improve the evidence of ESD's impact on additional outward indications of Meniere's disease.Alterations in necessary protein gly