https://www.selleckchem.com/pr....oducts/ganetespib-st
Mice previously colonised with these strains were protected against septicaemic pneumonia but, unlike mice colonised with the wild type strain, not against recolonisation. Colonisation with the and strains prevented subsequent septicaemia, but in contrast, to published data for encapsulated double mutant strains they did not prevent recolonisation with . These data suggest targeting the locus is a less effective option for creating live attenuated strains that prevent infections. Colonisation with the ∆cps/piaA and ∆cps/proA