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Altered neural activity based on the fractional amplitude of low-frequency fluctuations (fALFF) has been reported in patients with diabetes. However, whether fALFF can differentiate healthy controls from diabetic animals under anesthesia remains unclear. The study aimed to elucidate the changes in fALFF in a rat model of diabetes under isoflurane anesthesia. The first group of rats (n = 5) received a single intraperitoneal injection of 70mg/kg streptozotocin (STZ) to cause the development of diabetes. The second group of rats (n = 7) re
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