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aging 78% and 45%, respectively. Dietary treatments were similar in MFPS (0.89 mm) and MRT for both liquid (23.7 h) and solid (27.4 h) phase material. These results indicate an improvement in DMD for reduced lignin alfalfa hay when fed to adult horses, with no change in forage consumption, fecal particle size, or digesta retention time.Eukaryotic translation initiation factor 4E (eIF4E) mediates cap-dependent translation. Genetic and inhibitor studies show that eIF4E expression is required for the successful transition from maternal to