https://www.selleckchem.com/pr....oducts/nimbolide.htm
This review aims to give an update on recent findings related to the cardiac splicing factor RNA-binding motif protein 20 (RBM2 and RBM20 cardiomyopathy, a form of dilated cardiomyopathy caused by mutations in RBM20. While most research on RBM20 splicing targets has focused on titin (TTN), multiple studies over the last years have shown that other splicing targets of RBM20 including Ca /calmodulin-dependent kinase IIδ (CAMK2D) might be critically involved in the development of RBM20 cardiomyopathy. In this regard, loss of RBM20 caus
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