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and Purpose There were studies showing the positive effects of Tai Chi on sleep, fatigue, endurance, balance, anxiety and depression in rheumatologic diseases. The aim of this study was to investigate the effects of Tai Chi exercise program on trunk endurance, balance, sleep, fatigue, anxiety and depression in patients with systemic sclerosis (SSc). 28 patients were randomly divided into two groups as Tai Chi (n14, 53.35±10.86 years) and home exercise group (n14, 52.64±9.45 years). Trunk Lateral Endurance Test, Berg Balance Scale, Pittsb