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5% vs 59.9% among vaccinate at infancy, p less then .001) and more frequently attending postgraduate medical school (80.8% vs 57.5% among healthcare profession school, p less then .001). The multivariable logistic regression model showed that HBV vaccination at age of 12 was significantly and independently associated with protective titers (OR = 10.27, p = .019).The results agreed with literature on HBV vaccination, confirming the efficacy of vaccination after 20 years. In particular, our results suggest that adolescent adminis