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The differential expression pattern of the MRPS18family proteins suggests that they play various roles in cellular processes. The differential expression pattern of the MRPS18 family proteins suggests that they play various roles in cellular processes.The review presents modern ideas about tumor microenvironment, which most researchers recognize as the main "player" in tumor cell invasion, cell migration and metastasis. The current data on the main components of the stroma and the microenvironment, which play the role of the driving force