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The typical number of ClinVar considerable variants within the patients was 769.43, 16.50percent regarding the variations had been recognized by only 1 variant caller. Despite variations with considerable impact on clinical decision-making, the recognized variants are different for every algorithm. To work well with genetic variants within the clinical field, a strict standard for NGS pipelines is essential.The development of certain antiviral substances to SARS-CoV-2 is an urg