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RESEARCH QUESTION What valid guideline-based quality indicators can measure quality of care in early pregnancy assessment units (EPAU)? DESIGN The systematic RAND-modified Delphi method was used to develop an indicator set from four evidence-based guidelines. An international expert panel was assembled to extract recommendations from these guidelines to establish quality indicators. RESULTS A total of 119 recommendations were extracted. Eleven recommendations received a high median score and top five score above the 75th percentile and were select