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Responsible Breeders Never Sell German Shepherd Puppies For Sale in Switzerland Responsible breeders never sell their German Shepherd puppies to just anyone with cash in hand. This type of uncaring breeding practices could lead to genetic health and temperament problems that can result in thousands of dollars in vet bills and years of heartache and sorrow. Switzerland is a prime target for criminals posing as breeders and rescues. These wolves in sheep's clothing ta

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No systemic inflammation was found in cystitis-induced URO-OVA mice, nor was any inflammation found in wild-type C57BL/6 mice adoptively transferred with OVA-primed splenocytes. Along with bladder inflammation, URO-OVA mice demonstrated significantly increased pelvic nociceptive responses, voiding dysfunction, and upregulated mRNA expression levels for IFN-γ, tumor necrosis factor-α (TNF-α), and substance P precursor in the bladder. This model reproduces the histological and clinical features of human HIC, providing a novel mod