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In this viewpoint we therefore point out highly promising recent machine learning developments in proteomics, alongside some of the remaining challenges. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.Prostaglandin analogues (PG), beta-blockers (B or their combination (PG+B are used primarily to reduce the intraocular pressure (IOP) pathologically associated with glaucoma. Since, fibrosis of the trabecular meshwork (TM) is a major aetiological factor in glaucom