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This paper describes Hokkaido's cancer genomic medicine provision system, including its exit strategy, and the human resource development that serve as its foundation.The third-term Basic Plan to Promote Cancer Control Programs in Japan started in 2018. Preparation of the cancer genomic medicine has been newly demanded in this program. Since 2018, the Cancer Genome Medicine Core Base Hospitals( CGM-CBHs), the Cancer Genome Medicine Base Hospitals(CGM-BHs)and the Cancer Genome Medicine Cooperation Hospitals(CGM-CHs)were appointed by